The Syracuse Orange have battled Big East teams like Louisville, Connecticut and Pittsburgh and they have dealt with big men like Pitt's DeJuan Blair and UConn's Hasheem Thabeet.
Next up is Blake Griffin of the Oklahoma Sooners tonight in the South Regional semifinal.
Griffin has played even better in the postseason than he did in winning Big 12 player of the year. He's averaging 30.5 points and 15 rebounds in the first two NCAA Tournament wins, and the Player of the Year candidate has missed only seven shots.
Syracuse will counter Griffin with Jim Boeheim's 2-3 zone and a pair of 6-9 forwards in Arinze Onuaku and Rick Jackson.
Expect an offensive display since Syracuse ranked ninth in the country and led the Big East, averaging 80.4 points, while Oklahoma ranked 11th and put up 79.1 points per game.
Can the 1-point underdog Orange knock off another NCAA powerhouse?
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